Key takeaways
- "CJC-1295" names two molecules. With DAC is long-acting; without DAC is the same thing as Mod GRF 1-29.
- Our market lists CJC-1295 (without DAC) and Mod GRF 1-29 separately, at identical prices from identical vendor counts.
- Trials showed it raises growth hormone and IGF-1. They did not establish benefit for fat loss, muscle, recovery, sleep, or longevity.
- Raising a blood marker is not the same as improving an outcome, and this is the clearest example we track.
The name problem comes first
Before anything about evidence, you need to know which molecule someone is talking about. With CJC-1295 that's genuinely unclear, and the ambiguity is doing damage.
"CJC-1295" is used for two different compounds.
With DAC. The drug affinity complex is a modification that keeps the compound active far longer. This is the version our profile covers, listed under the aliases CJC-1295 with DAC and DAC:GRF.
Without DAC. A shorter-acting compound, and the same thing sold under the name Mod GRF 1-29.
Different durations, different behaviour, overlapping names. A forum post about "CJC-1295" often doesn't specify which, and the two aren't interchangeable.
Our own market shows the double-listing
Here's a concrete illustration from our price market, checked 25 July 2026.
| Listing | Price range | Vendors |
|---|---|---|
| CJC-1295 (without DAC) | $42.95 to $145.00 | 7 |
| Mod GRF 1-29 | $42.95 to $145.00 | 7 |
Identical range, identical vendor count, two separate rows.
That's what one compound listed under two names looks like in market data. Nothing sinister about it, since both names are in genuine use, and it's a good demonstration of how naming confusion propagates through a market until you can't count what's actually being sold.
If you're shopping, the practical consequence is direct: check whether a listing says with DAC or without, because those are not the same purchase.
How it's thought to work
CJC-1295 is a GHRH-receptor agonist.
GHRH is growth-hormone-releasing hormone, the signal your hypothalamus sends to tell the pituitary to release growth hormone. CJC-1295 mimics that signal.
The DAC version's design prolongs exposure, so the GH and IGF-1 stimulation lasts longer than the natural pulse would.
Our profile summarises it as an unapproved long-acting GHRH analog studied in small healthy-volunteer trials.1
What the trials actually showed, and what they didn't
This is the most useful thing on the page, and it's a distinction worth carrying to every peptide you look at.
Early trials demonstrated prolonged increases in growth hormone and IGF-1.
That's a real, measured, replicable finding. The compound does what its mechanism says it should. Blood levels of GH and IGF-1 go up and stay up.
They did not establish clinical benefit for fat loss, muscle gain, recovery, sleep, or longevity.
Both sentences are true at once, and the gap between them is the whole story.
| What was measured | What wasn't |
|---|---|
| Growth hormone levels | Fat loss |
| IGF-1 levels | Muscle gain |
| Duration of that effect | Recovery |
| Sleep quality | |
| Longevity |
GH and IGF-1 are surrogate markers. They're stand-ins for outcomes, chosen because they're easy to measure and because they're plausibly connected to the things people actually want.
Sometimes a surrogate holds up. Often it doesn't. Moving a number in a blood test is not the same as making someone better, and CJC-1295 is the clearest example we track of a compound that reliably does the first thing with no established evidence for the second.
We rate it low evidence with an early signal, in our research directory. That's a tier above the very-low compounds like BPC-157, precisely because the pharmacology is genuinely established. It just stops there.
More on this failure mode in why evidence maturity beats online momentum.
What the supply looks like
Our testing ledger holds one published lab record for CJC-1295 with DAC.3
One. A 5mg vial that measured 5.19mg at 99.288% purity, which is a tight result and tells you almost nothing about anything else on the market.
For the without-DAC version, we hold none at all.
Against that, 7 vendors list the without-DAC compound and more list the DAC version. A single certificate cannot describe a market, and this is among the thinnest evidence bases of anything we track.
When a seller does show you a certificate, check which molecule it names. A COA for the DAC version says nothing about a non-DAC vial, and our vendor checklist covers what else to look for.
Where CJC-1295 sits
Know which molecule you're reading about. With DAC and without DAC are different compounds, and the without-DAC one has a second name.
The pharmacology is real. It raises GH and IGF-1, durably, and that's been measured.
The benefits are not established. No clinical benefit for fat loss, muscle, recovery, sleep, or longevity, which covers essentially everything it's marketed for.
The supply is barely documented. One lab record for one of the two versions.
Marketing that presents a rise in growth hormone as though it were a proven result is exactly the kind of unsupported health claim regulators police.2
Next: ipamorelin, the compound it's most often stacked with. Profile with graded outcomes and sources: CJC-1295.
Frequently asked questions
What is the difference between CJC-1295 with and without DAC?
The drug affinity complex, or DAC, is a modification that extends how long the compound stays active in the body. With DAC it is long-acting. Without DAC it is a shorter-acting compound that is also sold under the name Mod GRF 1-29. They are different molecules with different durations, sold under overlapping names.
Is CJC-1295 FDA approved?
No. It is not approved for any use and is sold labelled for research only. Our profile describes it as an unapproved long-acting GHRH analog studied in small healthy-volunteer trials.
Does CJC-1295 build muscle or burn fat?
That has not been established. Early trials demonstrated prolonged increases in growth hormone and IGF-1, which are laboratory measurements rather than outcomes. Our profile states plainly that they did not establish clinical benefit for fat loss, muscle gain, recovery, sleep, or longevity.
Is CJC-1295 the same as Mod GRF 1-29?
Mod GRF 1-29 is the same compound as CJC-1295 without DAC. It is not the same as CJC-1295 with DAC. In our own price market the two names appear as separate listings carrying identical price ranges and identical vendor counts, which is what you would expect from one compound listed twice.
Read next
Educational information only. This article does not recommend a treatment, supplier, dose, or medical decision. See how we evaluate evidence.